Articles
Circadian Therapeutics and Arquimea Collaboration
Circadian Therapeutics and ARQUIMEA sign a collaboration agreement for the development of casein kinase 1 inhibitors for the treatment of diseases affecting the nervous system Co-development of molecules as an innovative treatment for nervous system diseases such as...
New CT Research Published
Adenosine integrates light and sleep signalling for the regulation of circadian timing in miceNew research, published today in Nature Communications by Circadian Therapeutics founders and collaborators, identifies an adenosine-based regulatory mechanism that allows...
Circadian Therapeutics Announce the Appointment of Dr. Mark Sampson
Circadian Therapeutics Ltd is delighted to announce the appointment of Dr Mark Sampson as Chief Executive Officer and Board Member of the Company, effective 1st July 2020. Most recently Chief Medical Officer of Shield Therapeutics PLC, Dr Sampson has had a...
Study Shows Circadian Clock Plays Unexpected Role in Neurodegenerative Diseases
In the study, NU researchers employed the fruit fly model of Huntington's disease, a well-studied model organism for both circadian rhythms and neurodegenerative diseases. The researchers knocked down the hop gene in fruit flies with the protein that causes...
10 Ways Circadian Rhythms Affect Your Health
Israeli researchers have uncovered fascinating facts about how the body clock impacts metabolism, mood, microbiome and much more. Disturbances to the circadian rhythm, or to the genes that produce the rhythm, can cause problems from low productivity and...
Study Finds Fat Cells Exhibit Circadian Rhythms Affecting Critical Metabolic Functions
Fat cells in the human body have their own internal clocks and exhibit circadian rhythms affecting critical metabolic functions, new research in the journal Scientific Reports, finds. Researchers led by Dr Jonathan Johnston from the University of Surrey...
New Research into Links Between Circadian Rhythms and Cancer
Virginia Tech Molecular Biologist Carla Finkielstein's new research confirms her earlier findings that, this is why night shift workers develop cancer at a higher rate. The bright light they’re exposed to at night confuses cancer suppressing molecules and cancer...
Circadian Rhythms, Epigenetics and Disease
Epigenetics is the study of heritable changes in gene expression (active versus inactive genes) that do not involve changes to the underlying DNA sequence — a change in phenotype without a change in genotype — which in turn affects how cells read the genes. Little...
Shift work for mothers associated with reduced foetal growth and longer pregnancies
Shift workers are at increased risk of developing type 2 diabetes and obesity, however the impact during pregnancy on maternal metabolism is unknown. New research published in The Journal of Physiology indicates shift work exposure in mothers can result in...
New Role for the Brain’s Support Cells in Controlling Circadian Rhythms
Astrocytes, ‘caretaker’ cells that surround and support neurons in the brain, play a much more important role in circadian rhythms, the body’s 24-hour internal clock, than previously understood. The Medical Research Council funded study found that these...