Circadian Therapeutics Ltd is delighted to announce the appointment of Dr Mark Sampson as Chief Executive Officer and Board Member of the Company, effective 1st July 2020. Most recently Chief Medical Officer of Shield Therapeutics PLC, Dr Sampson has had a...

  In the study, NU researchers employed the fruit fly model of Huntington's disease, a well-studied model organism for both circadian rhythms and neurodegenerative diseases. The researchers knocked down the hop gene in fruit flies with the protein that causes...

  Israeli researchers have uncovered fascinating facts about how the body clock impacts metabolism, mood, microbiome and much more. Disturbances to the circadian rhythm, or to the genes that produce the rhythm, can cause problems from low productivity and insomnia to...

  Fat cells in the human body have their own internal clocks and exhibit circadian rhythms affecting critical metabolic functions, new research in the journal Scientific Reports, finds. Researchers led by Dr Jonathan Johnston from the University of Surrey conducted...

Virginia Tech Molecular Biologist Carla Finkielstein's new research confirms her earlier findings that, this is why night shift workers develop cancer at a higher rate. The bright light they’re exposed to at night confuses cancer suppressing molecules and cancer...

 Epigenetics is the study of heritable changes in gene expression (active versus inactive genes) that do not involve changes to the underlying DNA sequence — a change in phenotype without a change in genotype — which in turn affects how cells read the genes.  Little...

  Shift workers are at increased risk of developing type 2 diabetes and obesity, however the impact during pregnancy on maternal metabolism is unknown. New research published in The Journal of Physiology indicates shift work exposure in mothers can result in reduced...

  Astrocytes, ‘caretaker’ cells that surround and support neurons in the brain, play a much more important role in circadian rhythms, the body’s 24-hour internal clock, than previously understood. The Medical Research Council funded study found that these star-shaped...

  Asthma exhibits a marked time of day variation in symptoms, airway physiology, and airway inflammation. This is also seen in chronic obstructive pulmonary disease (COPD), but to a lesser extent. Our understanding of how physiological daily rhythms are regulated by...

  Circadian rhythms are guided by internal clocks in cells that enable organisms to adapt to night and day cycles. Disruption of this cycle can lead to health problems in people, so scientists study cell behavior to see how the interrupted clock can cause diseases—an...