Articles

 Epigenetics is the study of heritable changes in gene expression (active versus inactive genes) that do not involve changes to the underlying DNA sequence — a change in phenotype without a change in genotype — which in turn affects how cells read the genes.  Little...

  Shift workers are at increased risk of developing type 2 diabetes and obesity, however the impact during pregnancy on maternal metabolism is unknown. New research published in The Journal of Physiology indicates shift work exposure in mothers can result in...

  Astrocytes, ‘caretaker’ cells that surround and support neurons in the brain, play a much more important role in circadian rhythms, the body’s 24-hour internal clock, than previously understood. The Medical Research Council funded study found that these...

  Asthma exhibits a marked time of day variation in symptoms, airway physiology, and airway inflammation. This is also seen in chronic obstructive pulmonary disease (COPD), but to a lesser extent. Our understanding of how physiological daily rhythms are regulated...

  Circadian rhythms are guided by internal clocks in cells that enable organisms to adapt to night and day cycles. Disruption of this cycle can lead to health problems in people, so scientists study cell behavior to see how the interrupted clock can cause...

  A new study by researchers at The University of Texas at Austin suggests such injuries could throw off the internal clock of the entire body’s daily activities, from hormones to sleep-wake schedules. The spinal cord helps transfer information between the body...

  "We were able to inhibit the growth of liver cancer in a mouse model by manipulating the circadian clock at the cellular level," said Kristin Eckel-Mahan, Ph.D., the study's senior author and an assistant professor with the Center for Metabolic and Degenerative...

    Innovative cardioprotective strategies are of imminent demand. Nonfatal myocardial ischemia (MI) poses a significant risk to patients undergoing major non-cardiac surgery and these non-cardiac surgeries account for around 8 million myocardial injuries...

  BBC Horizon investigated the body clock and it's effect on our behaviour. We all have a biological clock ticking away inside us that governs our daily rhythms. This affects our health as much as our diet and whether we exercise. So what can we do to manage this...

  Determining the state of an individual’s internal physiological clock has important implications for precision medicine, from diagnosing neurological disorders to optimizing drug delivery. To be useful, such a test must be accurate, minimally burdensome to the...